Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Ajoene is a sulfur-containing compound derived from garlic (Allium sativum) and is primarily formed during the crushing of garlic cloves. Its use for supporting or treating poor circulation is justified by a growing body of scientific evidence. Research has demonstrated that ajoene exhibits several biological activities that may benefit vascular health. Specifically, ajoene has been found to inhibit platelet aggregation, which is a critical factor in preventing the formation of blood clots that can impede circulation. This antithrombotic effect is attributed to ajoene’s ability to interfere with fibrinogen binding and the activation of platelet receptors.

In addition, ajoene possesses mild vasodilatory properties, which can help improve blood flow. Studies in both animal models and human platelet assays have shown ajoene to reduce the risk of thrombosis and to promote a healthier blood flow profile. Moreover, ajoene’s antioxidant and anti-inflammatory actions may further protect vascular endothelium and support overall circulatory health.

Despite these promising findings, most clinical evidence is preliminary, with much of the data coming from in vitro and animal studies. Human clinical trials are sparse but suggest that ajoene, as part of garlic extracts, may have a moderate effect on circulation, particularly in populations at risk for cardiovascular disease. As such, while scientific support exists, further robust clinical trials are needed to fully validate ajoene’s efficacy in treating poor circulation.

More about ajoene
More about Circulation (poor)

Other ingredients used for Circulation (poor)

Other health conditions supported by ajoene

Products containing ajoene