Evidence supporting the use of: Vitamin D
For the health condition: Chronic Obstructive Pulmonary Disorder

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin D has garnered scientific interest as a supportive therapy in Chronic Obstructive Pulmonary Disease (COPD). Several observational studies have reported that vitamin D deficiency is common among people with COPD, and lower serum vitamin D levels have been associated with increased disease severity, frequency of exacerbations, impaired lung function, and higher mortality. The rationale for supplementation stems from vitamin D’s immunomodulatory and anti-inflammatory effects, which could theoretically help in reducing airway inflammation and susceptibility to respiratory infections common in COPD.

Randomized controlled trials (RCTs) and meta-analyses have yielded mixed results. Some studies indicate that vitamin D supplementation may reduce the rate of moderate-to-severe COPD exacerbations, especially in patients with profound vitamin D deficiency (<10 ng/mL). However, the benefit appears much less or absent in those with higher baseline vitamin D levels. Other trials have found no significant improvement in lung function, quality of life, or all-cause mortality with supplementation. Current clinical guidelines do not recommend universal vitamin D supplementation for all COPD patients but suggest it may be considered for those with documented deficiency.

In summary, there is moderate scientific evidence (rating 3/5) supporting vitamin D supplementation in vitamin D-deficient individuals with COPD, particularly for reducing exacerbations, but the evidence is not strong enough to recommend it universally for all COPD patients.

More about vitamin D
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Other health conditions supported by vitamin D

Acne
Allergies (food)
Allergies (respiratory)
Alzheimer's Disease
Amenorrhea
Anemia
Anorexia
Apathy
Arrhythmia
Arteriosclerosis
Arthritis
Asthma
Autism
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Backache
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Body Building
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Calcium Deficiency
Cancer (natural therapy for)
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Cancer Treatment (reducing side effects)
Cardiovascular Disease
Celiac Disease
Chronic Obstructive Pulmonary Disorder
Colds (antiviral)
Colds (general)
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Colds (with fever)
Concentration (poor)
Concussions
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Congestive Heart Failure
Contagious Diseases
Convalescence
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Cramps (menstrual)
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Crohn's Disease
Cystic Breast Disease
Cystic Fibrosis
Dandruff
Debility
Dementia
Depression
Dermatitis
Diabetes
Diabetic Retinopathy
Erectile Dysfunction
Estrogen (low)
Fatigue
Fibroids (uterine)
Fibromyalgia Syndrome
Fibrosis
Grave's Disease
Grief and Sadness
Hair (loss or thinning)
Hair Care (general)
Hashimoto's Disease
Headache (cluster)
Heart (weakness)
Hypertension
Hypothyroid
Infection
Infection (bacterial)
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Infertility
Inflammation
Inflammatory Bowel Disorders
Influenza
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Irritable Bowel Syndrome
Itching
Knees (weak)
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Memory and Brain Function
Menopause
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Mental Illness
Metabolic Syndrome
Migraine
Miscarriage (prevention)
Mood Swings
Multiple Sclerosis
Muscle Tone (lack of)
Muscular Dystrophy
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PMS (general)
PMS Type D
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Pregnancy (herbs and supplements for)
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