Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Sichuan Fritillary (Fritillaria cirrhosa), known as Chuan Bei Mu in traditional Chinese medicine (TCM), has been used historically to treat coughs, phlegm, and lung-related conditions, including symptoms associated with Chronic Obstructive Pulmonary Disease (COPD). Its use is rooted primarily in TCM practices, where it is believed to "moisten the lungs," clear heat, and resolve phlegm. Several classical TCM texts recommend Chuan Bei Mu as a remedy for chronic cough and bronchial conditions, often in combination with other herbs.

Scientific research into Sichuan Fritillary’s efficacy for COPD is limited and mostly preclinical. Some studies have identified alkaloids, such as peimine and peiminine, with anti-inflammatory and antitussive properties in animal models, which could theoretically benefit respiratory conditions. However, robust clinical trials in humans with COPD are lacking, and the existing evidence is not sufficient to confirm efficacy or safety for this indication by modern standards. Thus, the main justification for its use in COPD comes from tradition, with moderate support from laboratory studies but insufficient clinical evidence. Overall, it remains a traditional remedy with a low to moderate evidence rating for COPD.

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