Cluster Fig (Ficus racemosa) has a history of use in traditional medicine systems, particularly Ayurveda, for a variety of health conditions, including metabolic and cardiovascular disorders. Its use for managing high cholesterol is primarily rooted in traditional practice rather than robust scientific validation. Ayurvedic texts often mention the bark, fruit, and leaves of Ficus racemosa as remedies for conditions associated with metabolism and heart health, which may include high cholesterol, though the references tend to be generalized rather than specific to lipid profiles.

A limited number of preclinical studies have investigated the hypolipidemic effect of Ficus racemosa extracts in animal models. Some animal studies have reported a reduction in total cholesterol and triglyceride levels after administration of extracts from the bark or fruit. However, these studies are few, often lack rigorous controls, and there is a notable absence of high-quality human clinical trials to confirm efficacy and safety for this indication.

In summary, the use of Cluster Fig for high cholesterol is primarily supported by traditional use, with only preliminary scientific exploration. The current evidence base is insufficient to warrant strong recommendations for its use in cholesterol management, and more robust clinical research would be necessary to validate its efficacy and safety.