Evidence supporting the use of: Alpha-Lipoic Acid
For the health condition: Cholesterol (high)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Alpha-lipoic acid (ALA) is an antioxidant that has been studied for its potential effects on lipid profiles, including cholesterol levels. Several small-scale clinical trials and animal studies have investigated its impact. Some research suggests that ALA supplementation may modestly reduce total cholesterol, LDL cholesterol, and triglyceride levels, particularly in people with metabolic syndrome or type 2 diabetes. Proposed mechanisms include improved insulin sensitivity and reduced oxidative stress, both of which can indirectly influence lipid metabolism.

However, the evidence is not robust. Meta-analyses of randomized controlled trials show only small to moderate reductions in cholesterol parameters, and results are sometimes inconsistent. The quality of the studies varies, with some having methodological limitations such as small sample sizes, short durations, and variations in dosage. Major health organizations do not currently recommend ALA as a primary treatment for high cholesterol.

In summary, while there is some scientific evidence suggesting a potential lipid-lowering effect of alpha-lipoic acid, the overall strength of the evidence is limited. It may have a minor adjunctive role for certain individuals, but it is not considered a standard or standalone therapy for high cholesterol.

More about Alpha-Lipoic Acid
More about Cholesterol (high)

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Products containing Alpha-Lipoic Acid

We currently have no products on Caring Sunshine that contain this ingredient.