Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Thaumatococcus daniellii, commonly known as the miracle fruit or African serendipity berry, has a long history of use in West African ethnomedicine. Its leaves and other plant parts have been traditionally applied in the management of gastrointestinal disturbances, including diarrhea, dysentery, and sometimes cholera. The use for cholera is based largely on empirical traditional medical practices rather than rigorous scientific validation. There are anecdotal and ethnobotanical reports documenting its use for symptoms resembling cholera, such as severe diarrhea, but there is a lack of robust clinical or laboratory studies directly demonstrating its efficacy against Vibrio cholerae infection or its toxins. Most available studies focus on the plant’s general antimicrobial, antioxidant, and anti-inflammatory properties, or its use as a sweetener (thaumatin). As such, while there is some traditional justification for its application in treating diarrhea or cholera-like symptoms, the scientific evidence remains minimal and indirect. Therefore, the use of Thaumatococcus daniellii against cholera is primarily supported by tradition, with a weak evidence base and should not be considered a replacement for proven medical treatments.

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