Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Sodium is scientifically validated as a critical component in the treatment of cholera, particularly in the context of oral rehydration therapy (ORT). Cholera causes severe diarrhea and vomiting, leading to rapid dehydration and loss of essential electrolytes, including sodium. The World Health Organization (WHO) and numerous clinical studies have established that the administration of an oral rehydration solution (ORS), which contains sodium chloride along with glucose and other electrolytes, dramatically reduces mortality and morbidity associated with cholera. The underlying scientific principle is that the co-transport of sodium and glucose across the intestinal wall facilitates efficient water absorption, even when the intestines are affected by cholera toxin. This mechanism was elucidated in the 1960s and revolutionized cholera treatment, reducing case fatality rates from over 30% to less than 1% where ORT is used. The sodium content in ORS is precisely formulated to replace what is lost in diarrheal stools, prevent hyponatremia, and maintain proper physiological function. Numerous randomized controlled trials and field studies in cholera-endemic regions have confirmed the efficacy and safety of sodium-containing ORS. Thus, the use of sodium in cholera treatment is strongly supported by robust scientific evidence and remains a cornerstone of global cholera management protocols.

More about Sodium
More about Cholera

Other ingredients used for Cholera

Other health conditions supported by Sodium

Products containing Sodium