Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Sichuan Fritillary (Fritillaria cirrhosa), known as "Chuan Bei Mu" in Traditional Chinese Medicine (TCM), is primarily used for its expectorant and cough-suppressant properties. Its inclusion in formulas for cholera is based on traditional practice rather than modern scientific validation. In the context of TCM, "cholera" (huòluàn) often referred to a syndrome involving vomiting, diarrhea, and dehydration, not strictly the Vibrio cholerae infection as defined in modern medicine. Historical materia medica texts such as the "Compendium of Materia Medica" (Bencao Gangmu) sometimes mention Fritillaria species in compound prescriptions for symptoms resembling cholera, likely due to their purported ability to clear heat and resolve phlegm. However, there is no robust clinical or pharmacological evidence from contemporary biomedical research to support the use of Sichuan Fritillary specifically for the treatment or management of cholera (Vibrio cholerae infection). Modern research on Fritillaria focuses on its alkaloids for respiratory conditions, not gastrointestinal infections. Therefore, the support for this use is almost entirely traditional, and the strength of evidence is minimal.

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