Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Salt (sodium chloride) has strong scientific validation for its use in the treatment of cholera. Cholera causes severe diarrhea and vomiting, leading to rapid loss of fluids and electrolytes, particularly sodium and chloride ions. This can result in dehydration and potentially death if not treated promptly. The cornerstone of cholera treatment is oral rehydration therapy (ORT), which involves administering a precise mixture of salt (sodium chloride), glucose, potassium, and bicarbonate or citrate dissolved in clean water. The World Health Organization (WHO) and numerous clinical studies have shown that this solution is highly effective in replacing lost fluids and electrolytes, dramatically reducing mortality rates from cholera. The mechanism relies on the sodium-glucose co-transport system in the small intestine, which allows for efficient absorption of sodium and water when glucose is present. This principle was discovered in the 1960s and revolutionized the management of diarrheal diseases. While salt alone is not sufficient—glucose is also required for optimal absorption—sodium chloride is an essential component of the oral rehydration solution. Historical and contemporary clinical evidence strongly supports this practice, and oral rehydration solutions are recommended by major health authorities worldwide as first-line therapy for cholera.

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