Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Neem (Azadirachta indica) has been traditionally used in various systems of medicine, especially in Ayurveda, for a range of ailments, including infections and gastrointestinal disturbances. Its use in cholera, however, is primarily based on traditional and folk remedies rather than robust scientific evidence. Historical texts and ethnobotanical reports indicate that neem leaves or extracts were sometimes used in rural Indian communities as part of home remedies for symptoms associated with cholera, such as diarrhea and intestinal infections. The rationale stems from neem’s well-documented antimicrobial and anti-inflammatory properties, which may provide some relief in gastrointestinal infections.

However, there is a lack of high-quality clinical studies or scientific validation specifically examining neem’s efficacy against Vibrio cholerae, the bacterium responsible for cholera. Most available evidence is limited to in vitro studies demonstrating neem’s general antibacterial activity, with no direct clinical correlation to cholera treatment. Modern guidelines for cholera management do not recommend neem, and its use is not supported by contemporary medical practice. In summary, neem’s use for cholera is rooted in traditional practice with minimal scientific endorsement, and it should not replace established medical therapies.

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