Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Laptedenia (likely referring to Laptadenia species, such as Laptadenia hastata) has traditional use in African folk medicine, including as a treatment for cholera and other gastrointestinal issues. Ethnobotanical surveys from West Africa, especially in Nigeria and Senegal, document the use of the leaves and stems for managing diarrhea, dysentery, and sometimes cholera. The traditional preparations typically involve decoctions or infusions of the plant parts. The rationale underlying these practices is often empirical, based on generations of observed results rather than scientific validation.

However, scientific evidence supporting its efficacy specifically against cholera is minimal. Some in vitro studies have shown that Laptadenia hastata extracts have antimicrobial activity against a range of pathogens, including some bacteria associated with gastrointestinal infections. These studies do not directly address Vibrio cholerae, the causative agent of cholera, nor do they provide clinical trial data in humans. As such, while the traditional use is well-documented, scientific validation is lacking, and the evidence for effectiveness against cholera is weak.

In summary, Laptadenia is used traditionally for conditions like cholera, but the support for this use is largely anecdotal and ethnobotanical. No robust clinical or laboratory evidence currently confirms its safety or efficacy for treating cholera specifically.

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