Evidence supporting the use of: Allium (unspecified)
For the health condition: Cholera

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Allium species, particularly garlic (Allium sativum) and onion (Allium cepa), have a long history of use in traditional medicine for a variety of infectious diseases, including cholera. Historical records from various cultures—such as Ayurveda, Unani, and traditional European herbal medicine—mention the use of Allium preparations to treat symptoms of gastrointestinal infections like diarrhea and dysentery, which are prominent in cholera. The rationale for their use was based on observed antimicrobial and antiseptic properties. However, while some laboratory studies have demonstrated that compounds in Allium (e.g., allicin) possess in vitro antibacterial activity (including some activity against Vibrio cholerae, the causative agent of cholera), there is no robust clinical evidence from controlled human trials that supports the effectiveness of Allium for treating or preventing cholera. Modern cholera treatment relies on rehydration therapy and antibiotics when necessary. Therefore, while the use of Allium for cholera has strong traditional roots and some plausible biochemical basis, scientific validation in the context of clinical efficacy for cholera is lacking.

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