Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Prickly Ash, which can refer to several species in the Zanthoxylum genus (such as Zanthoxylum americanum or Zanthoxylum clava-herculis), has a long history of use in traditional herbal medicine in North America. Among Native American tribes and early European settlers, Prickly Ash bark and berries were used to treat a variety of ailments, including digestive issues, toothache, and, occasionally, symptoms related to poor circulation and chest pain (often described historically as “heart pain” or “pain in the breast”). The rationale for its use in chest pain was typically based on its perceived ability to stimulate blood flow and act as a “blood mover” or circulatory tonic, rather than any specific cardiovascular mechanism understood today. However, the evidence is entirely anecdotal and rooted in tradition, with no robust scientific studies or clinical trials validating its efficacy for actual chest pain (angina or cardiac pain). Modern herbal medicine references sometimes repeat this traditional use, but contemporary medical sources do not recognize Prickly Ash as a validated treatment for chest pain, and there is no scientific consensus or substantial research supporting its safety or effectiveness for this purpose.

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