Evidence supporting the use of: Vitamin E (vitamin E acetate)
For the health condition: Chemotherapy (reducing side effects)

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E (particularly in the form of vitamin E acetate) has been investigated for its potential to reduce certain side effects of chemotherapy, primarily chemotherapy-induced peripheral neuropathy (CIPN), a common and often debilitating complication. Some randomized controlled trials and meta-analyses have explored vitamin E supplementation as a means to prevent or reduce the severity of CIPN, especially with agents like cisplatin and paclitaxel. For example, a 2014 meta-analysis (Zhang et al., 2016) suggested that vitamin E supplementation may offer a modest protective effect against CIPN. However, the evidence remains mixed, with some studies showing benefit and others not replicating these results or raising concerns about potential negative interactions with chemotherapy efficacy.

While vitamin E is known for its antioxidant properties, which theoretically may counteract some of the oxidative damage induced by chemotherapeutic agents, the clinical relevance and safety of this approach remain under debate. Current oncology guidelines do not universally recommend routine use of vitamin E to reduce chemotherapy side effects, largely due to insufficient high-quality evidence and concerns that antioxidants might interfere with the anti-tumor effects of chemotherapy.

In summary, there is some scientific investigation into vitamin E’s role in mitigating chemotherapy side effects, particularly neuropathy, but the overall quality and consistency of evidence is limited. More rigorous and larger scale studies are needed before vitamin E can be routinely recommended for this purpose.

More about Vitamin E (vitamin E acetate)
More about Chemotherapy (reducing side effects)

Other ingredients used for Chemotherapy (reducing side effects)

aloe vera
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
amino acids
anthocyanins
astaxanthin
astragalus
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
black cumin
black currant
blueberry
branched-chain amino acids
bromelain
cannabis sativa oil
chamomile
chlorella
coenzyme Q10 (CoQ10)
colostrum
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
fish oil
ginger
grape
green tea
hemp oil
l-alanyl-l-glutamine
l-carnosine
l-cysteine
l-glutamine
l-glutathione
l-glycine
l-taurine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus lactis
lactoferrin
lentinula edodes mycelia
licorice root
lion's mane
luteolin
marine lipid
matcha
melatonin
milk thistle
n-acetyl-cysteine (NAC)
pectin
phytocannabinoids
pomegranate
protein
pyridoxal-5-phosphate (P-5-P)
quercetin
reishi mushroom
resveratrol
saccharomyces boulardii
selenium
shiitake mushroom
spirulina
streptococcus thermophilus
tributyrin
turkey tail mushroom
vitamin B6
vitamin C
vitamin E
whey protein
zinc
coix
herbal blend (proprietary)
soy isoflavones
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Alpha Glucans
Antrodia camphorata
AHCC
Alpha-Lipoic Acid
Alpha lactalbumin
Acemannan
Alkylglycerols
Bifidobacterium
Baikal Skullcap
Bifidobacterium adolescentis
Boswellic Acid
Bifidobacterium animalis
Bifidobacteria
BCAA
benzyl isothiocyanate
Caryophyllene
Codonopsis
Curcuminoid
C-Phycocyanin
Cannabidiol
Clostridium butyricum
Cannabigerol
Dithiolthiones
Ergothioneine
Folinic Acid
Fucoidan
Glutamine
Glutathione
Milk Protein
Mistletoe

Products containing Vitamin E (vitamin E acetate)

We currently have no products on Caring Sunshine that contain this ingredient.