Evidence supporting the use of: Vitamin B6 (not specified)
For the health condition: Chemotherapy (reducing side effects)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin B6 (pyridoxine) has some scientific support for use in reducing specific chemotherapy-induced side effects, particularly peripheral neuropathy and hand-foot syndrome. Several randomized controlled trials and meta-analyses have explored pyridoxine supplementation to mitigate neurotoxicity associated with chemotherapeutic agents such as cisplatin, vincristine, and taxanes. The evidence is mixed: some studies report a reduction in symptoms of peripheral neuropathy, while others find minimal or no benefit. Notably, pyridoxine is frequently recommended for the management of hand-foot syndrome (palmar-plantar erythrodysesthesia) caused by drugs like capecitabine and 5-fluorouracil, with some clinical guidelines supporting its use for this indication, though evidence quality is moderate.

Vitamin B6 is generally well-tolerated at recommended doses, but high doses can cause sensory neuropathy, so supplementation should be supervised. There is limited evidence for its role in managing other chemotherapy side effects, such as nausea or anemia, unless the patient is deficient. Overall, while not universally effective for all patients or all side effects, Vitamin B6 is scientifically validated (with moderate evidence) for reducing certain chemotherapy-induced toxicities, particularly neuropathy and hand-foot syndrome.

More about Vitamin B6 (not specified)
More about Chemotherapy (reducing side effects)

Other ingredients used for Chemotherapy (reducing side effects)

aloe vera
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
amino acids
anthocyanins
astaxanthin
astragalus
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
black cumin
black currant
blueberry
branched-chain amino acids
bromelain
cannabis sativa oil
chamomile
chlorella
coenzyme Q10 (CoQ10)
colostrum
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
fish oil
ginger
grape
green tea
hemp oil
l-alanyl-l-glutamine
l-carnosine
l-cysteine
l-glutamine
l-glutathione
l-glycine
l-taurine
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus lactis
lactoferrin
lentinula edodes mycelia
licorice root
lion's mane
luteolin
marine lipid
matcha
melatonin
milk thistle
n-acetyl-cysteine (NAC)
pectin
phytocannabinoids
pomegranate
protein
pyridoxal-5-phosphate (P-5-P)
quercetin
reishi mushroom
resveratrol
saccharomyces boulardii
selenium
shiitake mushroom
spirulina
streptococcus thermophilus
tributyrin
turkey tail mushroom
vitamin B6
vitamin C
vitamin E
whey protein
zinc
coix
herbal blend (proprietary)
soy isoflavones
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Alpha Glucans
Antrodia camphorata
AHCC
Alpha-Lipoic Acid
Alpha lactalbumin
Acemannan
Alkylglycerols
Bifidobacterium
Baikal Skullcap
Bifidobacterium adolescentis
Boswellic Acid
Bifidobacterium animalis
Bifidobacteria
BCAA
benzyl isothiocyanate
Caryophyllene
Codonopsis
Curcuminoid
C-Phycocyanin
Cannabidiol
Clostridium butyricum
Cannabigerol
Dithiolthiones
Ergothioneine
Folinic Acid
Fucoidan
Glutamine
Glutathione
Milk Protein
Mistletoe

Products containing Vitamin B6 (not specified)

We currently have no products on Caring Sunshine that contain this ingredient.