Evidence supporting the use of: Reishi mushroom
For the health condition: Chemotherapy (reducing side effects)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Reishi mushroom (Ganoderma lucidum) has a long history of use in traditional Chinese medicine, including as a supportive treatment during illness. In recent decades, several preclinical and clinical studies have explored its potential benefits for cancer patients undergoing chemotherapy, particularly regarding immune system support and the mitigation of side effects such as fatigue, insomnia, and loss of appetite.

Scientific evidence for reishi’s efficacy in reducing chemotherapy side effects is modest but suggestive. Some small randomized controlled trials and observational studies indicate that reishi extracts may improve quality of life for cancer patients by enhancing immune responses (e.g., increasing natural killer cell activity) and reducing symptoms like fatigue and nausea. A 2016 systematic review of randomized controlled trials found that while reishi may offer some benefit as an adjunct to chemotherapy, the evidence is inconsistent and often limited by small sample sizes and methodological weaknesses. Most studies report that reishi is generally well-tolerated, though rare side effects such as gastrointestinal upset have been noted.

In summary, the use of reishi mushroom to reduce chemotherapy side effects is supported by preliminary scientific evidence, but the overall quality and quantity of data are limited. Larger, well-designed clinical trials are needed to confirm its efficacy and safety. Its use is best considered as a complementary approach rather than a replacement for standard supportive care.

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Acemannan
AHCC
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coix
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Haematococcus pluvialis
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herbal blend (proprietary)
hericium mushroom
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spirulina
streptococcus thermophilus
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