Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Aloe vera is commonly used as an adjunctive treatment for chemotherapy-induced side effects, particularly for skin reactions such as radiation dermatitis and oral mucositis. The rationale for its use is based on both its historical application for wound healing and emerging, though limited, scientific studies. Aloe vera gel contains polysaccharides, glycoproteins, and other bioactive compounds believed to promote tissue repair, reduce inflammation, and exert moisturizing effects. Several small clinical trials and observational studies have investigated aloe vera's efficacy in managing side effects of chemotherapy and radiotherapy. Results are mixed: some studies suggest that topical aloe vera may help reduce the severity of radiation-induced skin damage and oral mucositis, while others show no significant benefit compared to standard care or placebo. For instance, a randomized study published in the Journal of Clinical Oncology found no significant difference in the prevention of radiation dermatitis with aloe vera gel compared to placebo. Conversely, some smaller studies and patient reports have noted subjective improvements in comfort and symptom relief. Overall, while aloe vera is widely used and considered safe for topical application, robust scientific evidence supporting its effectiveness in reducing chemotherapy side effects is limited and inconsistent. Therefore, it is best described as having some scientific validation, but with only modest evidence (rating: 2/5).

More about aloe vera
More about Chemotherapy (reducing side effects)

Other ingredients used for Chemotherapy (reducing side effects)

Other health conditions supported by aloe vera

Products containing aloe vera

Nature's Sunshine CleanStart Mild
Nature's Sunshine Aloe Vera (Freeze Dried)
Nature's Sunshine Aloe Vera Gel
Nature's Sunshine Aloe Vera Juice
Nature's Sunshine Aloe Vera Juice (Whole Leaf)
Nature's Sunshine Liquid Cleanse