Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Clinoptilolite, a natural zeolite mineral, is primarily used for its ion-exchange and adsorption properties. Scientifically, clinoptilolite has demonstrated the ability to bind certain heavy metals and toxins due to its microporous structure. Several in vitro and animal studies have shown that clinoptilolite can adsorb toxic metals like lead, cadmium, and mercury, reducing their absorption in the gastrointestinal tract and facilitating their excretion. For example, studies in rats have shown decreased accumulation of lead and cadmium in tissues when clinoptilolite is administered orally. Additionally, some research has indicated a reduction in the toxic effects of certain chemicals, such as ammonia and aflatoxins, through clinoptilolite supplementation in animal models. However, data from well-controlled human clinical trials are limited. Most evidence comes from laboratory or animal studies, and while some small-scale human studies exist, they often lack rigorous methodology or sufficient participant numbers to draw firm conclusions. Regulatory bodies like the European Food Safety Authority (EFSA) recognize clinoptilolite as safe for certain uses, such as feed additives, but do not endorse its use for treating chemical poisoning in humans due to insufficient clinical evidence. Therefore, while there is a scientific rationale and some preliminary evidence supporting its potential use in chemical poisoning, the strength of the evidence is moderate at best, warranting a rating of 2.

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