Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Curcumin, a polyphenolic compound derived from turmeric (Curcuma longa), has attracted scientific interest for its potential role in preventing or treating cervical dysplasia, a precancerous condition often linked to persistent human papillomavirus (HPV) infection. Laboratory and animal studies have demonstrated that curcumin exhibits anti-inflammatory, antioxidant, and anticancer properties. Specifically, it has been shown to inhibit proliferation and induce apoptosis in cervical cancer cell lines, as well as interfere with HPV oncoprotein expression (notably E6 and E7), which are key drivers of cervical dysplasia and cancer progression. Small pilot clinical trials and in vitro studies have suggested that topical or oral curcumin might reduce cervical lesions or HPV load, but these studies are limited by small sample sizes, short durations, and methodological variability.

Despite promising preclinical evidence and a plausible biological mechanism, robust, large-scale randomized controlled trials in humans are lacking. Thus, current scientific evidence is preliminary (rated 2 out of 5), and curcumin cannot yet be recommended as a standalone or primary treatment for cervical dysplasia. Nevertheless, its low toxicity profile and traditional use in other inflammatory conditions have encouraged further research. Until more conclusive clinical evidence is available, curcumin should be considered a complementary rather than primary intervention for cervical dysplasia.

More about curcumin
More about Cervical Dysplasia

Other ingredients used for Cervical Dysplasia

Other health conditions supported by curcumin

Products containing curcumin

Nature's Sunshine Turmeric Curcumin (Formerly CurcuminBP)