Evidence supporting the use of: Bifidobacterium infantis
For the health condition: Celiac Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bifidobacterium infantis is considered to have some scientific rationale for use in supporting individuals with Celiac Disease, though the evidence is currently limited and mostly preliminary. Research demonstrates that people with Celiac Disease often have an altered gut microbiota, including a reduction in beneficial bacteria such as Bifidobacterium species. Some studies have shown that supplementation with Bifidobacterium infantis may help restore a healthier gut microbial balance and reduce inflammation in the intestines of those with Celiac Disease.

For example, a 2013 randomized, double-blind, placebo-controlled clinical trial published in the journal Alimentary Pharmacology & Therapeutics found that children with newly diagnosed Celiac Disease who received B. infantis supplements along with a gluten-free diet experienced some improvements in gut microbiota composition and a reduction in markers of intestinal inflammation, compared to those who received placebo. Another small study suggested that B. infantis supplementation could reduce symptoms of irritable bowel syndrome (IBS)-like symptoms in Celiac patients who continue to have symptoms despite a gluten-free diet.

However, while these studies are promising, they are small in scale and further research is needed to confirm the efficacy and safety of B. infantis as a supportive therapy for Celiac Disease. Thus, the use of B. infantis is based on emerging scientific evidence rather than historical tradition, and its role remains adjunctive rather than primary in Celiac Disease management.

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