Evidence supporting the use of: Bifidobacterium bifidum
For the health condition: Celiac Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bifidobacterium bifidum is a probiotic bacterium that has been investigated for its potential role in supporting gut health, including in individuals with Celiac Disease. The scientific rationale for its use is based on the observation that people with Celiac Disease often have altered gut microbiota, characterized by reduced levels of beneficial bacteria such as Bifidobacterium species. Several small-scale studies and preclinical research suggest that supplementation with B. bifidum may help restore a more balanced intestinal microbiome, which could, in theory, reduce inflammation and support gut barrier function in celiac patients.

A notable study (Primec et al., 2012) demonstrated that children with newly diagnosed Celiac Disease had lower counts of Bifidobacterium species, and that probiotic supplementation contributed to partial restoration of the gut microbial balance. Other research (e.g., Smecuol et al., 2013) has examined the use of bifidobacteria-containing probiotics in celiac patients on a gluten-free diet, finding some evidence for improvement in gastrointestinal symptoms and markers of inflammation. However, these studies are generally small, sometimes use mixed probiotic strains, and do not consistently show dramatic clinical benefits.

In summary, the use of B. bifidum for Celiac Disease is supported by preliminary scientific evidence suggesting a potential benefit in modulating gut microbiota and inflammation, but the quality and quantity of evidence are limited. Larger, high-quality clinical trials are needed to determine its true efficacy. Currently, the evidence is best characterized as promising but not definitive.

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