Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E (alpha-tocopheryl succinate) has been studied for its potential in supporting or treating cataracts, primarily due to its antioxidant properties. Cataracts are largely associated with oxidative stress in the lens of the eye, and antioxidants like vitamin E have been hypothesized to help prevent or slow their progression. Some epidemiological studies have noted that higher dietary intake or higher blood levels of vitamin E are associated with a reduced risk of cataract formation. However, large randomized controlled trials (RCTs), such as the Age-Related Eye Disease Study (AREDS) and other similar studies, have generally failed to show a significant benefit of vitamin E supplementation—alone or in combination with other antioxidants—in either preventing cataracts or slowing their progression.

Alpha-tocopheryl succinate is one of the ester forms of vitamin E and is used in supplements for its stability, but there is no evidence that this specific form is superior to others for eye health. The current consensus is that while vitamin E is an important dietary antioxidant, supplementation beyond the recommended dietary allowance does not appear to provide substantial benefit for cataract prevention or treatment in the general population. Thus, the use of vitamin E for cataracts is justified by a scientific rationale, but actual evidence from intervention trials is weak, meriting a rating of 2/5.

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