Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Flavonoids, a diverse group of plant compounds found in fruits, vegetables, tea, and other foods, have been traditionally used in various cultures for their general health benefits, particularly for eye health. The rationale for their use in cataracts is primarily based on their antioxidant properties, which are believed to help neutralize oxidative stress—a contributing factor in cataract formation. However, while laboratory and animal studies show that flavonoids can protect lens proteins from oxidative damage, robust clinical evidence in humans is lacking. Most of the support for using flavonoid mixtures in cataract prevention or treatment comes from traditional medicine and epidemiological observations suggesting higher dietary flavonoid intake is associated with lower cataract risk. Large-scale, randomized controlled trials specifically evaluating flavonoid mixtures for cataract prevention or treatment are absent, and authoritative clinical guidelines do not recommend their use for this purpose. Thus, while there is a plausible biological mechanism and some supportive population data, the evidence remains limited and primarily traditional rather than strongly scientific.

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