Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin C (ascorbic acid) has been investigated for its potential role in supporting cardiovascular health. Scientific interest originates from Vitamin C’s function as an antioxidant and its involvement in collagen synthesis, which is crucial for maintaining blood vessel integrity. Some observational studies have found associations between higher dietary Vitamin C intake and reduced risk of cardiovascular disease (CVD). Additionally, Vitamin C may help improve endothelial function and reduce blood pressure, both of which are important factors in cardiovascular health.

However, randomized controlled trials (RCTs) and meta-analyses have generally found that supplemental Vitamin C offers limited benefit in preventing major cardiovascular events like heart attacks or strokes, especially in well-nourished populations. For example, a 2013 review in the American Journal of Clinical Nutrition concluded that while Vitamin C supplementation could lower blood pressure modestly, evidence for reducing cardiovascular events was weak. The U.S. Preventive Services Task Force and other major guidelines do not recommend Vitamin C supplementation specifically for CVD prevention or treatment.

In summary, while there is some scientific rationale and observational evidence for Vitamin C’s cardiovascular benefits, high-quality clinical trials have not consistently demonstrated significant effects on cardiovascular outcomes. The evidence is modest (rated 2/5), and Vitamin C is not considered a primary therapy for cardiovascular disease.

More about Vitamin C (not specified)
More about Cardiovascular Disease

Other ingredients used for Cardiovascular Disease

Other health conditions supported by Vitamin C (not specified)

Products containing Vitamin C (not specified)