Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Thyroid hormone (typically levothyroxine, a synthetic form of thyroxine/T4) has a documented and scientifically validated role in the management of certain cardiovascular conditions, but only in specific contexts—primarily in patients with hypothyroidism (underactive thyroid). Hypothyroidism is associated with several adverse cardiovascular effects, including bradycardia (slow heart rate), increased peripheral vascular resistance, elevated cholesterol levels, and increased risk of atherosclerosis and heart failure. Numerous clinical studies have demonstrated that treating hypothyroidism with thyroid hormone replacement can reverse or mitigate these cardiovascular risks and symptoms. For example, normalization of thyroid hormone levels can improve lipid profiles, cardiac contractility, and overall cardiac function.

However, thyroid hormone is not used as a treatment for cardiovascular disease in patients with normal thyroid function (euthyroid individuals), and excessive replacement can be dangerous, potentially causing arrhythmias, angina, and worsening heart failure. Thus, the use of thyroid hormone in cardiovascular disease is justified only when the disease is secondary to hypothyroidism. There is no evidence supporting thyroid supplementation for cardiovascular benefit in patients with normal thyroid function. The rating of 3 reflects moderate evidence: strong for hypothyroid-associated cardiovascular disease, but not applicable or beneficial outside this context.

More about Thyroid
More about Cardiovascular Disease

Other ingredients used for Cardiovascular Disease

Other health conditions supported by Thyroid

Products containing Thyroid