Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Plantago, particularly Plantago ovata (psyllium), has some scientific evidence supporting its use in cardiovascular disease, mainly due to its high soluble fiber content. Psyllium husk is well-known for its cholesterol-lowering properties. Multiple clinical trials and meta-analyses have demonstrated that regular consumption of psyllium can reduce total cholesterol and low-density lipoprotein (LDL) cholesterol levels, both of which are important risk factors for cardiovascular disease. The mechanism is believed to involve the binding of bile acids in the intestine, which leads to increased excretion and consequently lower blood cholesterol levels as the body uses cholesterol to make more bile acids. The U.S. Food and Drug Administration (FDA) has approved a health claim for psyllium husk as part of a diet low in saturated fat and cholesterol to reduce the risk of heart disease. However, while the evidence for cholesterol-lowering is robust, direct evidence that Plantago or psyllium supplementation reduces cardiovascular events (such as heart attacks or strokes) is limited. Thus, while Plantago is not a direct treatment for cardiovascular disease, there is moderate scientific validation for its use as a dietary adjunct to support cardiovascular health by improving lipid profiles.

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