Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Curcuma, particularly Curcuma longa (turmeric), has been traditionally used in Ayurvedic and other traditional medicine systems for a variety of ailments, including cardiovascular complaints. More recently, scientific research has investigated curcumin, the primary active compound in turmeric, for potential cardiovascular benefits. Preclinical studies and some small clinical trials suggest that curcumin exhibits antioxidant, anti-inflammatory, and lipid-modulating properties, which may be beneficial in the context of cardiovascular disease (CVD). Some evidence indicates curcumin can improve endothelial function, reduce LDL cholesterol, and lower markers of inflammation such as C-reactive protein (CRP). However, these effects are generally modest, and most clinical trials to date have been small in scale, of short duration, or have methodological limitations. There is not yet strong, high-quality evidence from large randomized controlled trials demonstrating that Curcuma or curcumin supplementation provides significant clinical benefit in preventing or treating CVD in humans. Thus, while there is a scientific rationale and some preliminary evidence for its use, the overall evidence base remains limited and does not firmly establish Curcuma as an effective treatment for cardiovascular disease.

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