Evidence supporting the use of: Apple
For the health condition: Cardiovascular Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Apples are supported by scientific evidence for their potential benefits in cardiovascular disease (CVD) prevention and management. Epidemiological studies have consistently shown an association between higher apple consumption and reduced risk of CVD. The primary bioactive compounds in apples—dietary fiber (particularly soluble fiber like pectin) and polyphenols (such as flavonoids, including quercetin and catechin)—are thought to contribute to these effects. Soluble fiber helps lower total and LDL cholesterol by binding bile acids in the intestine, which leads to increased cholesterol clearance from the bloodstream. Polyphenols have antioxidant, anti-inflammatory, and endothelial function-improving properties, which may help reduce blood pressure and protect against atherosclerosis. Randomized controlled trials have demonstrated that regular apple consumption can modestly improve lipid profiles and markers of vascular health, although the effects are generally modest and may depend on baseline diet and apple variety.

While apples are not a substitute for standard medical therapies, their inclusion in a balanced diet is recommended by dietary guidelines for cardiovascular health. The strength of evidence is moderate (rated 3/5), as most studies are observational or short-term interventions, and there is variability in outcomes. Still, the consistency of findings and the plausible biological mechanisms justify their supportive role in cardiovascular disease prevention.

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acetyl l-carnitine
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algal oil
alpha-carotene
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amino acids
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anthocyanins
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arjun tree
astaxanthin
astragalus
basil
beet
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bilberry
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catechins
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chia seed
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citrus bioflavonoids
citrus sinensis (proprietary)
coenzyme Q10 (CoQ10)
conjugated linoleic acid (CLA)
cryptoxanthin
curcumin
d-alpha tocopherol
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flavonols
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l-arginine
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l-carnosine
l-citrulline
l-glycine
l-taurine
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linoleic acid (LA)
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lycopene
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