Evidence supporting the use of: Centella asiatica
For the health condition: Capillary Weakness

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Centella asiatica (also known as gotu kola) has a long history of traditional use for vascular health, but its application for capillary weakness is also supported by some scientific evidence. Modern research has focused on the plant’s triterpenoid compounds (notably asiaticoside and madecassoside), which have demonstrated positive effects on connective tissue and microcirculation. Several clinical trials and reviews suggest that Centella asiatica extracts can improve symptoms of chronic venous insufficiency (CVI) and reduce capillary permeability and fragility. For example, a double-blind, placebo-controlled study published in Angiology (1990) found that patients with venous hypertension treated with a Centella asiatica extract showed significant improvement in capillary filtration rate and microcirculatory parameters compared to placebo. Other studies have reported reduced edema and improved capillary resistance, likely due to enhanced synthesis of collagen and mucopolysaccharides in vascular walls. However, while these results are promising, the number of high-quality, large-scale randomized controlled trials remains limited. Most existing studies involve proprietary extracts and relatively short durations. Thus, while Centella asiatica is commonly used and appears effective for capillary fragility and related vascular conditions, further robust clinical research would be valuable to confirm and clarify its benefits.

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