Evidence supporting the use of: Rutosides
For the body system: Capillaries
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Rutosides, also known as rutin, are a group of flavonoid compounds found in various plants, most notably in buckwheat, citrus fruits, and certain berries. Their use to support the capillaries and vascular health has been investigated in both traditional and scientific contexts. Scientific studies suggest that rutosides exhibit antioxidant, anti-inflammatory, and vasoprotective properties. Clinical trials, particularly in Europe, have examined their efficacy in treating chronic venous insufficiency, capillary fragility (such as in patients with purpura or easy bruising), and hemorrhoids.
In these studies, rutosides have been shown to reduce capillary permeability and increase capillary resistance, which can help decrease swelling (edema) and improve symptoms related to weak capillaries. The European Medicines Agency recognizes rutosides as a traditional herbal medicinal product for the relief of symptoms of chronic venous insufficiency, based on a well-established use in Europe. Some randomized controlled trials have demonstrated modest improvements in symptoms like leg swelling and discomfort.
However, the overall quality of evidence is moderate, with some studies limited by small sample sizes or methodological weaknesses. Thus, while rutosides are not a miracle cure, there is a reasonable scientific basis for their use in supporting capillary health, especially as an adjunct to other therapies. More rigorous, large-scale studies would help clarify their efficacy further.
Other ingredients that support Capillaries
Aescinalpha-glycosyl isoquercitrin
anthocyanidins
anthocyanins
anthocyanosides
apocynin
apple
Aronia melanocarpa
ashitaba
asiaticoside
astragalin
astragalus
baicalein
Baikal Skullcap
benfotiamine
berry
bilberry
bioflavonoids
black currant
blueberry
butcher's broom
capers
capsicum
cayenne pepper
Centella asiatica
Centella triterpenes
Chinese salvia root
chokeberry
Citrus
citrus bioflavonoids
coca
Collinsonia
coumarin
cranesbill
cyanidin
cypress
danshen
delphinidin
dextran
diosmetin
Diosmin
eicosapentaenoic acid
epicatechin
Erigeron
escin
Fagopyrum
fatty acids
fish oil
flavanols
flavanones
flavans
flavoglycosides
flavones
flavonoids
flavonols
flavonones
fruit
garlic bulb
ginkgo biloba
ginkgo flavone glycoside
ginkgoheteroside
ginkgolides
Ginkgoside
gotu kola
grape
Gypenoside
hawthorn
herbal blend (proprietary)
hesperidin
horse chestnut
Hyperoside
Immortelle
Japanese sophora
L-arginine
leucoanthocyanidins
Ligusticum
Ligustrazin
linden
lingzhi
Mineral ascorbate
Nattokinase
Oligomeric proanthocyanidins
onion
orange
pagoda tree
Pentacyclic triterpenoids
Periwinkle
phenolic compounds
Phenylpropanoids
Phosphate ascorbate
pine bark
Polydatin
polymethoxylated flavones
polyphenols
prickly ash
proanthocyanidins
procyanidin
procyanidol
punicalagins
purslane
Pycnogenol
quercetin
rue
Ruscogenins
Ruscus
rutin
Rutosides
Salmon Oil
Salvianolic acid
Scotch Broom
shepherd's purse
Stone Root
Sweet Clover
Taxifolin
terpene lactones
Terpenoids
Troxerutin
Vincamine
vitamin B
vitamin C
vitamin E
vitamin K
Vitexin
Witch Hazel
Xantinol Nicotinate
Yarrow
Yarrow
Yumberry
