Evidence supporting the use of: Rue
For the body system: Capillaries
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Rue (Ruta graveolens) has a long history of use in traditional herbal medicine, including European folk medicine, where it was employed for a variety of ailments. One traditional application was to support capillary health and reduce capillary fragility—likely due to its perceived ability to enhance blood circulation and reduce bruising. Historic herbal texts mention rue as a remedy for "weak blood vessels" and to "strengthen the capillaries," especially in the context of varicose veins or easy bruising. These uses were based largely on empirical observation rather than clinical research.
Scientifically, rue contains several bioactive compounds, such as rutin and other flavonoids, which are known to have some effects on capillary permeability and vascular strength. Rutin, for example, has been studied for its potential to support capillary integrity. However, while rutin itself is validated in some studies, there is limited direct clinical evidence that the whole rue plant or its extracts significantly benefit capillary health in humans. Additionally, rue can be toxic in higher doses and is not widely recommended in modern phytotherapy for this purpose.
In summary, rue's use for capillary support is rooted mainly in tradition, with a modest foundation in the presence of bioactive constituents, but lacks robust scientific validation for this specific application.
Other ingredients that support Capillaries
Aescinalpha-glycosyl isoquercitrin
anthocyanidins
anthocyanins
anthocyanosides
apocynin
apple
Aronia melanocarpa
ashitaba
asiaticoside
astragalin
astragalus
baicalein
Baikal Skullcap
benfotiamine
berry
bilberry
bioflavonoids
black currant
blueberry
butcher's broom
capers
capsicum
cayenne pepper
Centella asiatica
Centella triterpenes
Chinese salvia root
chokeberry
Citrus
citrus bioflavonoids
coca
Collinsonia
coumarin
cranesbill
cyanidin
cypress
danshen
delphinidin
dextran
diosmetin
Diosmin
eicosapentaenoic acid
epicatechin
Erigeron
escin
Fagopyrum
fatty acids
fish oil
flavanols
flavanones
flavans
flavoglycosides
flavones
flavonoids
flavonols
flavonones
fruit
garlic bulb
ginkgo biloba
ginkgo flavone glycoside
ginkgoheteroside
ginkgolides
Ginkgoside
gotu kola
grape
Gypenoside
hawthorn
herbal blend (proprietary)
hesperidin
horse chestnut
Hyperoside
Immortelle
Japanese sophora
L-arginine
leucoanthocyanidins
Ligusticum
Ligustrazin
linden
lingzhi
Mineral ascorbate
Nattokinase
Oligomeric proanthocyanidins
onion
orange
pagoda tree
Pentacyclic triterpenoids
Periwinkle
phenolic compounds
Phenylpropanoids
Phosphate ascorbate
pine bark
Polydatin
polymethoxylated flavones
polyphenols
prickly ash
proanthocyanidins
procyanidin
procyanidol
punicalagins
purslane
Pycnogenol
quercetin
rue
Ruscogenins
Ruscus
rutin
Rutosides
Salmon Oil
Salvianolic acid
Scotch Broom
shepherd's purse
Stone Root
Sweet Clover
Taxifolin
terpene lactones
Terpenoids
Troxerutin
Vincamine
vitamin B
vitamin C
vitamin E
vitamin K
Vitexin
Witch Hazel
Xantinol Nicotinate
Yarrow
Yarrow
Yumberry
