Evidence supporting the use of: Proanthocyanidins
For the body system: Capillaries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Proanthocyanidins, a class of polyphenolic compounds found in foods such as grapes, berries, and pine bark, have been researched for their effects on vascular health, including support for capillaries. Several studies have shown that proanthocyanidins, particularly those derived from grape seed extract and French maritime pine bark (Pycnogenol), can help strengthen capillary walls, reduce capillary permeability, and improve microcirculation. These effects are thought to be due to their antioxidant properties and their ability to stabilize collagen and elastin, which are important structural proteins in blood vessel walls. Clinical trials in humans have demonstrated that supplementation with proanthocyanidins can reduce symptoms associated with capillary fragility, such as bruising and edema, particularly in conditions like chronic venous insufficiency and diabetic retinopathy. However, while the evidence is promising, the number and size of high-quality randomized controlled trials are still somewhat limited. Most studies support their use as an adjunct in vascular health, rather than a primary therapy. Overall, the use of proanthocyanidins for capillary support is scientifically justified, with moderate evidence primarily based on mechanistic studies, small clinical trials, and meta-analyses.

More about proanthocyanidins
More about Capillaries

Other ingredients that support Capillaries

alpha-glycosyl isoquercitrin
anthocyanins
apple
astragalus
bilberry
black currant
blueberry
butcher's broom
Chinese salvia root
chokeberry
citrus bioflavonoids
fish oil
flavonols
garlic bulb
ginkgo biloba
gotu kola
grape
onion
hawthorn
hesperidin
horse chestnut
Japanese sophora
L-arginine
Nattokinase
orange
phenolic compounds
pine bark
quercetin
rutin
vitamin B
vitamin C
vitamin E
vitamin K
Water
capsicum
lingzhi
Yarrow
Yarrow
prickly ash
sodium salt
terpene lactones
polyphenols
purslane
shepherd's purse
herbal blend (proprietary)
cayenne pepper
ashitaba
asiaticoside
Aronia melanocarpa
Aescin
anthocyanidins
anthocyanosides
apocynin
astragalin
Baikal Skullcap
baicalein
benfotiamine
berry
bioflavonoids
coumarin
Centella triterpenes
cyanidin
Citrus
Centella asiatica
coca
capers
cypress
cranesbill
Collinsonia
Diosmin
danshen
delphinidin
dextran
diosmetin
epicatechin
Erigeron
eicosapentaenoic acid
escin
fruit
flavonoids
fatty acids
flavanones
Fagopyrum
flavoglycosides
flavans
flavonones
flavanols
flavones
Gypenoside
ginkgolides
ginkgo flavone glycoside
Ginkgoside
ginkgoheteroside
Hyperoside
Immortelle
linden
Ligustrazin
leucoanthocyanidins
Ligusticum
Mineral ascorbate
Oligomeric proanthocyanidins
Phenylpropanoids
pagoda tree
procyanidol
procyanidin
Pentacyclic triterpenoids
Phosphate ascorbate
Polydatin
proanthocyanidins
Periwinkle
punicalagins
Pycnogenol
polymethoxylated flavones
rue
Ruscus
Ruscogenins
Rutosides
Salmon Oil
Salvianolic acid
Scotch Broom
Sweet Clover
Stone Root
Terpenoids
Taxifolin
Troxerutin
Vincamine
Vitexin
Witch Hazel
Xantinol Nicotinate
Yumberry

Products containing proanthocyanidins

We currently have no products on Caring Sunshine that contain this ingredient.