Evidence supporting the use of: Polyphenol (unspecified)
For the body system: Capillaries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Polyphenols are a class of naturally occurring compounds found abundantly in plants, such as fruits, vegetables, tea, and wine. Their use to support capillary health is primarily justified by scientific evidence. Research indicates that polyphenols, particularly flavonoids (a subgroup), exhibit vasoprotective effects. They help maintain capillary integrity and reduce capillary fragility, largely through their antioxidant and anti-inflammatory properties. For example, studies have shown that flavonoids like rutin and quercetin can reduce capillary permeability and strengthen the capillary walls, which is beneficial in conditions such as chronic venous insufficiency or easy bruising. Additionally, polyphenols may improve endothelial function, reduce oxidative stress, and inhibit platelet aggregation, all of which contribute to better vascular health. Some clinical trials have found that supplementation with polyphenol-rich extracts (such as those from grapes or citrus fruits) can decrease symptoms of capillary fragility and improve microcirculatory function. However, while the evidence is promising, it is largely based on studies of specific polyphenols or polyphenol-rich plant extracts, and not on "unspecified" polyphenol mixtures. The magnitude of benefit and optimal dosing are still being clarified. Therefore, the evidence is rated as moderate (3/5), reflecting supportive but not definitive data, especially when considering polyphenols as a broad, unspecified category.

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