Evidence supporting the use of: Polyphenol (unspecified)
For the body system: Capillaries
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Polyphenols are a class of naturally occurring compounds found abundantly in plants, such as fruits, vegetables, tea, and wine. Their use to support capillary health is primarily justified by scientific evidence. Research indicates that polyphenols, particularly flavonoids (a subgroup), exhibit vasoprotective effects. They help maintain capillary integrity and reduce capillary fragility, largely through their antioxidant and anti-inflammatory properties. For example, studies have shown that flavonoids like rutin and quercetin can reduce capillary permeability and strengthen the capillary walls, which is beneficial in conditions such as chronic venous insufficiency or easy bruising. Additionally, polyphenols may improve endothelial function, reduce oxidative stress, and inhibit platelet aggregation, all of which contribute to better vascular health. Some clinical trials have found that supplementation with polyphenol-rich extracts (such as those from grapes or citrus fruits) can decrease symptoms of capillary fragility and improve microcirculatory function. However, while the evidence is promising, it is largely based on studies of specific polyphenols or polyphenol-rich plant extracts, and not on "unspecified" polyphenol mixtures. The magnitude of benefit and optimal dosing are still being clarified. Therefore, the evidence is rated as moderate (3/5), reflecting supportive but not definitive data, especially when considering polyphenols as a broad, unspecified category.
Other ingredients that support Capillaries
alpha-glycosyl isoquercitrinanthocyanins
apple
astragalus
bilberry
black currant
blueberry
butcher's broom
Chinese salvia root
chokeberry
citrus bioflavonoids
fish oil
flavonols
garlic bulb
ginkgo biloba
gotu kola
grape
onion
hawthorn
hesperidin
horse chestnut
Japanese sophora
l-arginine
nattokinase
orange
phenolic acids
pine bark
quercetin
rutin
vitamin B
vitamin C
vitamin E
vitamin K
water
capsicum
lingzhi
yarrow
yarrow
prickly ash
sodium salt
terpene lactones
polyphenols
purslane
shepherd's purse
herbal blend (proprietary)
cayenne pepper
ashitaba
Asiaticoside
Aronia melanocarpa
Aescin
anthocyanidins
anthocyanosides
Apocynin
Astragalin
Baikal Skullcap
Baicalein
Benfotiamine
berry
Bioflavonoids
Coumarin
Centella triterpenes
Cyanidin
Citrus
Centella asiatica
Coca
Capers
cypress
Cranesbill
Collinsonia
Diosmin
Danshen
Delphinidin
Dextran
Diosmetin
epicatechin
Erigeron
Eicosapentaenoic Acid
Escin
Periwinkle
Other body systems supported by Polyphenol (unspecified)
ArteriesBlood
Brain
Capillaries
Circulatory System
Digestive System
Gastrointestinal Tract
Gums
Heart
Hepatic System
Immune System
Intestinal System
Joints
Kidneys
Large Intestines (Colon)
Liver
Lungs
Mitochondria
Muscles
Nerves
Prostate
Respiratory System
Skin
Small Intestines
Stomach
Urinary System
Veins