Evidence supporting the use of: Horse chestnut
For the body system: Capillaries

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Horse chestnut (Aesculus hippocastanum) seed extract has a documented history of use for supporting vascular health, particularly in the capillaries and veins. Its primary active component, aescin (or escin), has been studied for its effects on chronic venous insufficiency (CVI), a condition characterized by poor blood flow and capillary leakage in the legs. Several randomized controlled trials and meta-analyses have shown that horse chestnut seed extract can significantly improve symptoms associated with CVI, such as leg swelling, pain, and heaviness, when compared to placebo. The extract is believed to help strengthen capillary walls, reduce capillary permeability, and promote venous tone, which collectively supports capillary function and reduces edema.

A 2012 Cochrane Review concluded that horse chestnut seed extract is more effective than placebo for treating symptoms of CVI, with effects comparable to compression stockings in some studies. The mechanism is thought to involve aescin inhibiting enzymes that break down capillary walls and reducing inflammation. There is less evidence for its use in other capillary-related disorders, but for venous insufficiency and related capillary dysfunction, the scientific support is robust. However, horse chestnut should be used with caution, as raw seeds and some preparations can be toxic if not properly processed.

More about horse chestnut
More about Capillaries

Other ingredients that support Capillaries

alpha-glycosyl isoquercitrin
anthocyanins
apple
astragalus
bilberry
black currant
blueberry
butcher's broom
Chinese salvia root
chokeberry
citrus bioflavonoids
fish oil
flavonols
garlic bulb
ginkgo biloba
gotu kola
grape
onion
hawthorn
hesperidin
horse chestnut
Japanese sophora
L-arginine
Nattokinase
orange
phenolic compounds
pine bark
quercetin
rutin
vitamin B
vitamin C
vitamin E
vitamin K
Water
capsicum
lingzhi
Yarrow
Yarrow
prickly ash
sodium salt
terpene lactones
polyphenols
purslane
shepherd's purse
herbal blend (proprietary)
cayenne pepper
ashitaba
asiaticoside
Aronia melanocarpa
Aescin
anthocyanidins
anthocyanosides
apocynin
astragalin
Baikal Skullcap
baicalein
benfotiamine
berry
bioflavonoids
coumarin
Centella triterpenes
cyanidin
Citrus
Centella asiatica
coca
capers
cypress
cranesbill
Collinsonia
Diosmin
danshen
delphinidin
dextran
diosmetin
epicatechin
Erigeron
eicosapentaenoic acid
escin
fruit
flavonoids
fatty acids
flavanones
Fagopyrum
flavoglycosides
flavans
flavonones
flavanols
flavones
Gypenoside
ginkgolides
ginkgo flavone glycoside
Ginkgoside
ginkgoheteroside
Hyperoside
Immortelle
linden
Ligustrazin
leucoanthocyanidins
Ligusticum
Mineral ascorbate
Oligomeric proanthocyanidins
Phenylpropanoids
pagoda tree
procyanidol
procyanidin
Pentacyclic triterpenoids
Phosphate ascorbate
Polydatin
proanthocyanidins
Periwinkle
punicalagins
Pycnogenol
polymethoxylated flavones
rue
Ruscus
Ruscogenins
Rutosides
Salmon Oil
Salvianolic acid
Scotch Broom
Sweet Clover
Stone Root
Terpenoids
Taxifolin
Troxerutin
Vincamine
Vitexin
Witch Hazel
Xantinol Nicotinate
Yumberry

Other body systems supported by horse chestnut

Arteries
Blood
Capillaries
Circulatory System
Lymphatics
Rectum
Veins

Products containing horse chestnut

Nature's Sunshine Vari-Gone