Ginkgo biloba has been traditionally used in herbal medicine, but there is also some scientific investigation into its effects on the circulatory system, including the capillaries. Ginkgo’s primary active constituents—flavonoids and terpenoids—are thought to exert antioxidant and vasodilatory effects, which may support microcirculation. Several laboratory and animal studies indicate that ginkgo extract can reduce capillary permeability and fragility, likely due to its antioxidant properties and effects on vascular tone (Smith JV, Luo Y, 2004). Some clinical studies suggest that ginkgo may improve peripheral blood flow and microcirculation, particularly in patients with peripheral arterial disease or certain cognitive disorders, which are sometimes linked to capillary dysfunction (Kleijnen & Knipschild, 1992). However, the quality of evidence is variable, with some trials showing modest benefit and others showing little effect.

Most systematic reviews conclude that while there is plausible scientific rationale and some evidence for capillary support, the effects are modest, and more high-quality research is needed to make definitive recommendations. Thus, the use of ginkgo biloba to support capillary health is supported by some scientific evidence, but the overall rating for its efficacy based on current research is low to moderate.