Evidence supporting the use of: Flavones (various)
For the body system: Capillaries
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Flavones are a subclass of flavonoids, a group of polyphenolic compounds widely found in fruits, vegetables, and medicinal plants. Scientific research supports their use for supporting capillary health, primarily due to their antioxidant, anti-inflammatory, and vascular-protective properties. Several studies have shown that flavones such as diosmin, hesperidin, and apigenin can help strengthen capillary walls, reduce capillary permeability, and improve microcirculation. For instance, diosmin and hesperidin are routinely used in Europe to manage chronic venous insufficiency and related vascular disorders, including capillary fragility and varicose veins.
Clinical trials and meta-analyses suggest that these flavones can decrease symptoms such as leg swelling, heaviness, and cramps, likely by reducing inflammation and oxidative stress in capillary endothelial cells. Mechanistically, flavones inhibit the breakdown of capillary walls by scavenging free radicals and modulating inflammatory mediators. However, most of the evidence is focused on certain specific flavones, and efficacy may vary among different compounds in this class. While the evidence is not overwhelmingly strong across all flavones and all populations, a moderate scientific basis exists for using certain flavones to support capillary health.
Other ingredients that support Capillaries
alpha-glycosyl isoquercitrinanthocyanins
apple
astragalus
bilberry
black currant
blueberry
butcher's broom
Chinese salvia root
chokeberry
citrus bioflavonoids
fish oil
flavonols
garlic bulb
ginkgo biloba
gotu kola
grape
onion
hawthorn
hesperidin
horse chestnut
Japanese sophora
L-arginine
Nattokinase
orange
phenolic compounds
pine bark
quercetin
rutin
vitamin B
vitamin C
vitamin E
vitamin K
Water
capsicum
lingzhi
Yarrow
Yarrow
prickly ash
sodium salt
terpene lactones
polyphenols
purslane
shepherd's purse
herbal blend (proprietary)
cayenne pepper
ashitaba
asiaticoside
Aronia melanocarpa
Aescin
anthocyanidins
anthocyanosides
apocynin
astragalin
Baikal Skullcap
baicalein
benfotiamine
berry
bioflavonoids
coumarin
Centella triterpenes
cyanidin
Citrus
Centella asiatica
coca
capers
cypress
cranesbill
Collinsonia
Diosmin
danshen
delphinidin
dextran
diosmetin
epicatechin
Erigeron
eicosapentaenoic acid
escin
fruit
flavonoids
fatty acids
flavanones
Fagopyrum
flavoglycosides
flavans
flavonones
flavanols
flavones
Gypenoside
ginkgolides
ginkgo flavone glycoside
Ginkgoside
ginkgoheteroside
Hyperoside
Immortelle
linden
Ligustrazin
leucoanthocyanidins
Ligusticum
Mineral ascorbate
Oligomeric proanthocyanidins
Phenylpropanoids
pagoda tree
procyanidol
procyanidin
Pentacyclic triterpenoids
Phosphate ascorbate
Polydatin
proanthocyanidins
Periwinkle
punicalagins
Pycnogenol
polymethoxylated flavones
rue
Ruscus
Ruscogenins
Rutosides
Salmon Oil
Salvianolic acid
Scotch Broom
Sweet Clover
Stone Root
Terpenoids
Taxifolin
Troxerutin
Vincamine
Vitexin
Witch Hazel
Xantinol Nicotinate
Yumberry
