Evidence supporting the use of: Flavans
For the body system: Capillaries

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Flavans, a subgroup of flavonoids including catechins and proanthocyanidins, are plant-derived polyphenolic compounds found in foods such as tea, cocoa, grapes, and certain fruits. There is substantial scientific evidence supporting their role in promoting capillary health. Flavans have demonstrated antioxidant, anti-inflammatory, and vasoprotective properties in both animal and human studies. Specifically, oligomeric proanthocyanidins (OPCs), a type of flavan, have been shown to strengthen capillary walls, reduce capillary permeability, and improve microcirculation. Clinical trials have found that flavan-rich extracts (for example, from grape seeds or pine bark) can reduce symptoms of chronic venous insufficiency and edema, conditions linked to capillary fragility.

A 2014 systematic review in the Journal of Clinical Medicine concluded that proanthocyanidin supplementation improved capillary resistance and reduced edema in patients with chronic venous disorders. Additionally, the antioxidant capacity of flavans helps protect endothelial cells from oxidative stress, thus maintaining capillary integrity. While more research is warranted for specific dosage and long-term effects, the current scientific literature provides a robust foundation for the use of flavans to support capillary and vascular health.

More about flavans
More about Capillaries

Products containing flavans