Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Flavanones are a subclass of flavonoids, primarily found in citrus fruits such as oranges, lemons, and grapefruits. They include compounds like hesperidin, naringin, and eriocitrin. There is scientific evidence suggesting that flavanones can help support capillary health, largely due to their antioxidant, anti-inflammatory, and vasoprotective properties. Clinical studies have shown that hesperidin, often in combination with diosmin, can improve capillary resistance and decrease capillary permeability, which is beneficial in conditions such as chronic venous insufficiency and hemorrhoids. These effects are thought to arise from the ability of flavanones to strengthen capillary walls, reduce oxidative stress, and modulate inflammatory responses in vascular tissues.

A notable body of research, especially from Europe, supports the use of flavanone-rich extracts in the management of vascular disorders. For example, a 2015 review in the journal Phytotherapy Research highlighted that hesperidin and related flavanones could improve microcirculation and reduce symptoms such as leg swelling and heaviness. However, most clinical studies have been small or of moderate quality, and more large-scale, well-controlled trials are needed to conclusively establish efficacy. In summary, while traditional use exists, particularly in European phytotherapy, the application of flavanones for capillary support is primarily justified by scientific, though not definitive, evidence.

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