Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Fatty acids, particularly omega-3 polyunsaturated fatty acids (like EPA and DHA found in fish oil), have been studied for their effects on the vascular system, which includes capillaries. Scientific evidence supports that omega-3 fatty acids can improve endothelial function, reduce inflammation, and decrease blood viscosity, all of which contribute to healthier microcirculation and capillary integrity. Several randomized controlled trials and meta-analyses have shown that supplementation with omega-3 fatty acids can lower blood pressure, reduce markers of vascular inflammation, and improve overall vascular health. However, while there is moderate evidence for benefits at the level of larger blood vessels and overall cardiovascular health, direct evidence focusing specifically on capillary function is less robust. Some animal and in vitro studies suggest that omega-3s support capillary density and microvascular function, but human studies directly measuring capillary health are limited. Therefore, while the use of fatty acids to support the capillary system is grounded in a plausible biological mechanism and supported by moderate evidence, especially for cardiovascular and microvascular health generally, the evidence specifically for capillaries is not as strong as it is for larger blood vessels.

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