Evidence supporting the use of: Asiaticoside
For the body system: Capillaries
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Asiaticoside is a triterpenoid saponin compound isolated from Centella asiatica, a plant traditionally used in Asian medicine. There is a moderate level of scientific evidence supporting its use for capillary and microvascular health. Preclinical studies have shown that asiaticoside can promote collagen synthesis, strengthen vascular connective tissue, and enhance wound healing. These effects are believed to help improve capillary integrity and reduce capillary permeability, which can be beneficial in conditions like chronic venous insufficiency and microangiopathy.
Clinical data are limited but promising. Several small-scale human studies and meta-analyses of Centella asiatica extracts (which contain asiaticoside among other compounds) have reported improvements in symptoms such as edema and capillary fragility, likely due to effects on the extracellular matrix and vascular endothelial cells. However, most studies use plant extracts rather than purified asiaticoside, making it challenging to attribute the benefits solely to asiaticoside. Safety profiles are generally favorable.
In summary, the use of asiaticoside to support the capillaries is justified by both traditional use of the plant and a moderate but growing body of scientific research, particularly regarding its role in microvascular protection and connective tissue support. More large-scale, high-quality human trials are needed to firmly establish its efficacy and specific mechanisms.
Other ingredients that support Capillaries
alpha-glycosyl isoquercitrinanthocyanins
apple
astragalus
bilberry
black currant
blueberry
butcher's broom
Chinese salvia root
chokeberry
citrus bioflavonoids
fish oil
flavonols
garlic bulb
ginkgo biloba
gotu kola
grape
onion
hawthorn
hesperidin
horse chestnut
Japanese sophora
l-arginine
nattokinase
orange
phenolic acids
pine bark
quercetin
rutin
vitamin B
vitamin C
vitamin E
vitamin K
water
capsicum
lingzhi
yarrow
yarrow
prickly ash
sodium salt
terpene lactones
polyphenols
purslane
shepherd's purse
herbal blend (proprietary)
cayenne pepper
ashitaba
Asiaticoside
Aronia melanocarpa
Aescin
anthocyanidins
anthocyanosides
Apocynin
Astragalin
Baikal Skullcap
Baicalein
Benfotiamine
berry
Bioflavonoids
Coumarin
Centella triterpenes
Cyanidin
Citrus
Centella asiatica
Coca
Capers
cypress
Cranesbill
Collinsonia
Diosmin
Danshen
Delphinidin
Dextran
Diosmetin
epicatechin
Erigeron
Eicosapentaenoic Acid
Escin
Fruit
Flavonoids
Fatty acids
Flavanones
Fagopyrum
Flavoglycosides
Flavans
Flavonones
Flavanols
Flavones
Ginkgolides
Ginkgo Flavone Glycoside
Ginkgoside
Ginkgoheteroside
Periwinkle
Other body systems supported by Asiaticoside
ArteriesBrain
Capillaries
Circulatory System
Gums
Nerves
Skin