Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Anthocyanidins are a class of flavonoids found in many fruits and vegetables, especially those with red, blue, or purple pigmentation (e.g., berries, grapes). There is moderate scientific evidence that anthocyanidins may help support the health of capillaries and the vascular system. Preclinical studies have shown that anthocyanidins possess antioxidant and anti-inflammatory properties, which can help stabilize the walls of capillaries, reduce capillary permeability, and prevent oxidative damage to blood vessels. Clinical studies, although limited, suggest that anthocyanidin-rich extracts (such as those from bilberry or grape seed) can improve symptoms associated with capillary fragility, such as microbleeds, edema, or bruising, and may benefit conditions like chronic venous insufficiency. A 2015 review in the journal Phytotherapy Research highlighted that anthocyanins (closely related to anthocyanidins) improved microcirculation and capillary resistance in several small human trials. However, the evidence is not yet robust or entirely consistent; larger, well-controlled clinical trials are needed to establish definitive benefits and optimal dosages. Overall, current research provides a moderate level of support for the use of anthocyanidins in supporting capillary health.

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