Evidence supporting the use of: Vitamin D3
For the health condition: Cancer Treatment (reducing side effects)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin D3 has been investigated for its possible supportive role in cancer treatment, particularly for reducing treatment-related side effects and improving quality of life. Observational studies have found that vitamin D deficiency is common among cancer patients and may be associated with worse outcomes and increased side effects from treatments such as chemotherapy and radiation. Some clinical trials suggest that supplementation may help alleviate symptoms like fatigue, muscle weakness, and mood disturbances, which are common in cancer patients. Additionally, vitamin D is important for bone health, and supplementation can reduce the risk of osteoporosis in patients receiving hormone therapies or steroids that weaken bones.

However, randomized controlled trials (RCTs) specifically evaluating vitamin D3 supplementation to reduce cancer treatment side effects have produced mixed results. While some studies report modest improvements in well-being and reductions in certain side effects, others find no significant benefit. Current guidelines from oncology societies recognize vitamin D supplementation as reasonable for patients with documented deficiency but do not recommend routine high-dose use solely for side effect reduction in cancer therapy.

Overall, there is limited but emerging scientific evidence supporting vitamin D3 for mitigating some side effects of cancer treatment, primarily in patients who are deficient. More robust, large-scale RCTs are needed to clarify its efficacy for this purpose.

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Other ingredients used for Cancer Treatment (reducing side effects)

acetyl l-carnitine
akkermansia muciniphila
algal oil
aloe vera
alpha-ketoglutarate (AKG)
amino acids
ashwagandha
astaxanthin
astragalus
bacillus coagulans
bacillus subtilis
basil
beet
berberine
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broccoli
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butyrate triglyceride
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Chinese salvia root
chlorella
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citrus oil
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coating
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cuspidatum root
cyclodextrin
d-alpha tocopherol
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dong quai root
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eleuthero
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knotweed
jujube
kale
l-carnitine
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lactobacillus acidophilus
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ashitaba
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