Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Neem tree (Azadirachta indica) has a long history of use in traditional medicine, particularly in India and Southeast Asia, where it has been employed for its anti-inflammatory, antimicrobial, and purported anticancer properties. In recent years, preliminary scientific studies have investigated neem extracts in the context of cancer and cancer treatment side-effect management. Laboratory studies (in vitro and some in vivo using animal models) have demonstrated that neem extracts and compounds such as nimbolide and azadirachtin can exert cytotoxic effects on cancer cells, modulate immune responses, and possess antioxidant properties. These attributes provide a theoretical basis for their potential to reduce chemotherapy-induced toxicity and support cancer therapy.

However, the majority of the evidence to date is preclinical, with only limited small-scale human studies or case reports. Some research suggests neem extracts may ameliorate chemotherapy-related side effects like oral mucositis or immunosuppression due to their anti-inflammatory and immunomodulatory effects. Nonetheless, robust, well-designed clinical trials in humans are lacking, and there are concerns about standardization, dosage, and possible interactions with conventional therapies.

In summary, while there is some scientific interest and early-stage evidence for neem's supportive use in cancer treatment, the current strength of evidence is weak (rated 2 out of 5), and its use should be approached cautiously, preferably under medical supervision and not as a substitute for established treatments.

More about neem tree
More about Cancer Treatment (reducing side effects)

Other ingredients used for Cancer Treatment (reducing side effects)

Other health conditions supported by neem tree

Products containing neem tree

Nature's Sunshine Blood Sugar Formula (Ayurvedic)