Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Chinese salvia root (Salvia miltiorrhiza, known as "Danshen") has a longstanding history in Traditional Chinese Medicine (TCM), where it is used to invigorate blood circulation, remove blood stasis, and support organ function. Its use in cancer care, specifically to reduce the side effects of cancer treatments such as chemotherapy and radiation, is primarily rooted in tradition rather than robust scientific evidence. In TCM, Danshen formulas are sometimes prescribed to alleviate fatigue, promote healing, and reduce inflammation associated with aggressive cancer therapies.

Some preliminary laboratory and animal studies have suggested that components of Danshen, such as tanshinones and salvianolic acids, have antioxidant, anti-inflammatory, and even potential anti-tumor activities. However, clinical trials in humans for cancer side effect mitigation are limited and of low methodological quality. Small pilot studies and case reports have reported possible benefits in reducing chemotherapy-induced cardiotoxicity and improving quality of life, but these findings are not yet substantiated by large-scale, rigorous clinical trials.

Overall, while Danshen is traditionally used in TCM to support cancer patients and mitigate treatment side effects, there is insufficient high-quality scientific evidence to recommend it broadly for this purpose. Its use remains primarily tradition-based, and patients should consult their healthcare provider before using Danshen, as it may interact with other medications and affect bleeding risk.

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