Evidence supporting the use of: Vitamin K
For the health condition: Calcium Deficiency
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Vitamin K is not used to treat calcium deficiency in the sense of increasing calcium intake or correcting low calcium blood levels directly. However, there is scientific evidence supporting its role in calcium metabolism and bone health, which is why it is sometimes included in supplements aimed at supporting calcium status. Vitamin K, especially in its K2 (menaquinone) form, acts as a cofactor for the carboxylation of osteocalcin, a protein involved in binding calcium to the bone matrix. This process helps ensure that calcium is deposited in bones rather than soft tissues, thereby supporting healthy bone mineralization and reducing the risk of vascular calcification.
Clinical studies have shown that vitamin K supplementation can improve bone mineral density and reduce fracture risk, particularly in populations at risk for osteoporosis. However, its use is more as an adjunct to calcium and vitamin D supplementation, rather than a primary treatment for calcium deficiency itself. The evidence supporting vitamin K's benefit in bone metabolism is moderate, with some meta-analyses and clinical trials demonstrating positive effects, though results can be variable depending on dosage, population, and form of vitamin K used. There is less evidence supporting the use of vitamin K for acute or classical calcium deficiency (hypocalcemia).
In summary, vitamin K is scientifically recognized for its synergistic role in calcium utilization and bone health, but is not a substitute for dietary calcium or treatment of hypocalcemia. Its inclusion in calcium supplements is justified by its supportive role in bone metabolism.
Other health conditions supported by vitamin K
Bleeding (external)Bleeding (internal)
Broken Bones
Bruises (healing)
Bruises (prevention)
Calcium Deficiency
Calcium Deposits
Cardiovascular Disease
Nose Bleeds
Osteoporosis
