Evidence supporting the use of: Strontium
For the health condition: Calcium Deficiency
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Strontium is an alkaline earth metal with chemical properties similar to calcium, and its compounds, particularly strontium ranelate, have been investigated for their effects on bone health. Strontium is not used as a direct treatment for calcium deficiency (hypocalcemia), but rather for bone-related conditions such as osteoporosis. The scientific rationale for strontium use is based on its ability to both decrease bone resorption and increase bone formation, leading to an overall increase in bone mineral density. Strontium ranelate has been shown in clinical trials to reduce the risk of vertebral and non-vertebral fractures in postmenopausal women with osteoporosis. However, strontium does not correct calcium deficiency itself and should not replace calcium supplementation in patients with hypocalcemia. Instead, its effects are due to its partial incorporation into bone in place of calcium, which alters bone mineral properties. Some studies suggest strontium may interfere with calcium metabolism, and excessive use may even contribute to hypocalcemia or other adverse effects. Regulatory agencies such as the European Medicines Agency have restricted its use due to cardiovascular risks. In summary, while there is scientific evidence supporting strontium’s role in osteoporosis management, there is little to no evidence for its use specifically to treat calcium deficiency. Its use for this indication is not recommended, and the evidence rating for supporting calcium deficiency is low.
