Evidence supporting the use of: Casein Protein
For the health condition: Calcium Deficiency

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Casein protein is scientifically recognized for its role in supporting calcium nutrition, primarily due to its high calcium content and its ability to enhance calcium absorption. Casein is the major protein in cow's milk, accounting for about 80% of its protein content, and is naturally bound to calcium and phosphate, forming casein micelles. These micelles facilitate the delivery of calcium in a bioavailable form. Several studies have shown that the consumption of casein protein increases calcium intake and can improve calcium balance, particularly in populations at risk for calcium deficiency such as adolescents, postmenopausal women, and the elderly. For example, a review in the American Journal of Clinical Nutrition (2003) discusses how dairy proteins, including casein, can enhance calcium retention and bone health.

However, while casein contributes meaningfully to overall dietary calcium intake and its absorption, it is not used as a standalone treatment for calcium deficiency. Instead, it is a supportive dietary component. The evidence rating is moderate (3/5) because casein’s benefit is well established as a source of dietary calcium, but its use is adjunct rather than therapeutic in calcium-deficiency states. Most clinical guidelines recommend direct calcium supplementation or increased dietary intake of calcium-rich foods (including those containing casein) for correcting deficiency.

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