Evidence supporting the use of: Capsaisin
For the health condition: Burning Feet or Hands

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Capsaicin, the active compound in chili peppers, is scientifically validated for use in treating burning sensations in the feet or hands, particularly those arising from neuropathic pain such as in diabetic neuropathy or postherpetic neuralgia. Capsaicin creams and patches work by depleting substance P, a neuropeptide involved in transmitting pain signals in the peripheral nervous system. Over time, repeated application leads to reduced pain sensation by desensitizing sensory neurons.

Multiple randomized controlled trials and meta-analyses have demonstrated that topical capsaicin can provide moderate relief for patients suffering from neuropathic pain, including burning sensations in the extremities. The American Academy of Neurology and other clinical guidelines recognize capsaicin as an option for localized neuropathic pain. Its use is not limited to traditional medicine; rather, it is grounded in contemporary pharmacology and clinical research.

However, the efficacy is not universal, and some patients may experience initial irritation or burning upon application, which usually diminishes with continued use. For burning feet or hands not related to neuropathic etiologies, evidence for capsaicin’s effectiveness is limited. Overall, capsaicin is a scientifically supported, though not universally effective, treatment for burning sensations due to specific neuropathic conditions.

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Products containing Capsaisin

We currently have no products on Caring Sunshine that contain this ingredient.