Pistacia integerrima, commonly known as kakad-sind or zebrawood, is widely used in traditional Ayurvedic and Unani medicine systems, primarily for respiratory ailments. The galls of this plant (abnormal outgrowths caused by insects) are especially prominent in these traditional practices, where they have been utilized for centuries as a remedy for cough, asthma, bronchitis, and other bronchial conditions. The rationale behind their use is largely based on empirical evidence and long-standing tradition rather than robust modern clinical trials.

Scientific studies on Pistacia integerrima are limited, but some preliminary research has identified the presence of bioactive compounds such as tannins, flavonoids, and phenolics, which may exhibit anti-inflammatory, antimicrobial, and antioxidant properties. A few in vitro and animal studies suggest bronchodilatory and antitussive effects, which could provide a pharmacological basis for its traditional use. However, these studies are not sufficient to conclusively validate its efficacy or safety in humans for bronchial support. There are no large-scale, randomized controlled trials or systematic reviews available to support its effectiveness for respiratory conditions.

In summary, the use of Pistacia integerrima gall for supporting the bronchial system is primarily justified by historical tradition, with limited scientific evidence that is promising but not definitive.