Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin C (ascorbic acid) has some scientific basis for use in supporting bone healing, mainly due to its essential role in collagen synthesis. Collagen is a crucial protein in bone matrix formation and repair. Deficiency in vitamin C (as seen in scurvy) leads to impaired collagen production and, consequently, poor wound and bone healing. Several animal studies and a few human observational studies suggest that adequate vitamin C intake may support bone healing processes. For instance, animal research demonstrates improved fracture healing with vitamin C supplementation, largely attributed to enhanced collagen formation and antioxidant effects. However, high-quality randomized controlled trials in humans are limited.

A small number of clinical studies have explored vitamin C supplementation in patients with fractures. Some report faster healing times or improved markers of bone formation, but the evidence is not consistent or robust. There are no major clinical guidelines recommending vitamin C supplementation solely for fracture healing in individuals who are not deficient. Most experts agree that maintaining adequate, but not excessive, vitamin C intake is important for overall bone health and recovery from fractures, particularly in populations at risk for deficiency. In summary, while vitamin C is biologically relevant to bone repair, scientific evidence for supplementation beyond dietary sufficiency to enhance fracture healing is modest.

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